Sunday, January 29

Microdosing of psychedelics

Pregnancy risks

Psychedelic drugs are getting more and more attention from both doctors and patients because they have been shown to help people with conditions like depression that don't respond to treatment improve their mental health in a way that lasts. Microdosing psychedelic drugs like LSD or psilocybin means taking a small amount, called a "sub-perceptual dose," that is much lower than the amount you would take to "trip" or have hallucinations.

Many people agree that taking small amounts of psychedelics can improve your mood, creativity, focus, productivity, and ability to understand other people. Or could the benefits be a result of what people expect? This means that most people who take a pill every day with the firm belief that it will make them happier and smarter will feel happier and smarter, no matter what's in the pill.

The inability to define microdosing for any psychedelic substance in a single, universally accepted way makes it difficult to conduct consistent research. One definition is about 1/5 to 1/20 of a dose used for recreation. (This is true based on anecdotal evidence; a medium-strength dose of psilocybin is 2 to 3 grams of dried mushrooms, and a microdose is usually around 0.3 grams.) One problem is that mushrooms are not regulated outside of clinical trials, so their strength can vary a lot. This isn't an exact science. In the same way, LSD is a substance that can't be seen, smelled, or tasted. It usually comes in the form of a liquid or a piece of paper that can be put under the tongue.

Since it is illegal and not regulated, there is no good way to know how much you are taking unless you get it from a very trustworthy source. LSD is a very strong drug that stays in your body for a long time. You don't want to take more than you're supposed to. Also, psychedelics like psilocybin and LSD can cause physiological tolerance. This could mean that even if microdosing does help, staying at the same dose might not be as helpful.

Is microdosing safe? We don't know as much about safety as we could because, starting in the late 1960s, the War on Drugs stopped a lot of research into psychedelics. In the last five to ten years, this research has been brought back up to speed, and many medical centers are doing research on psychedelics. Most people think that small amounts of psilocybin are safe, and indigenous people have used it for hundreds of years. But if someone takes too much, it can lead to a scary or even traumatic experience.

Psilocybin is a chemical that is made from almost 200 kinds of mushrooms. The mushrooms must come from a reliable source. There are a lot of different kinds of mushrooms in nature, and some of them can look very similar to each other. However, some mushrooms are poisonous and can hurt your liver, making you sick or even killing you.

If psychedelics were legal, would that make them safer? 
Some psychedelic drugs, like psilocybin and MDMA, may be fully legalized for medical use under supervision in the next few years, say experts in the field (Ecstasy). Some policymakers and public health experts think that these psychedelics would be safer if they were not illegal and if they were grown and made in a way that was supervised and controlled. At the local level, psychedelics are no longer illegal in at least one state (Oregon) and many cities across the country.

Some people who support decriminalization want psychedelics to be safer and easier to get. This could mean that they don't have to see a doctor to get a prescription or be under medical supervision when they use them. Skeptics are concerned that unrestricted access to these drugs will harm people with mental illnesses or cause people who are vulnerable to develop a mental illness such as psychosis.

It is important to point out that people with serious mental illnesses like schizophrenia or bipolar disorder should only use psychedelic drugs with extreme caution, if at all. For safety reasons, these people are usually not allowed to take part in studies with psychedelic drugs.

A variety of facts support the use of microdosing of psychedelics. 
In short, we don't know yet. Some studies show that microdosing has a real and important benefit, while others are not as convincing and show little to no benefit. In a recent study, 953 people who took small amounts of psilocybin and 180 people who didn't take any found "small to medium improvements in mood and mental health that were generally the same across gender, age, and the presence of mental health problems." This study and others like it seem to back up the claims of many people who say that microdosing has helped them in some way.

In one case, researchers did a randomized controlled study, which is the best kind of proof because it gets rid of the placebo effect. The researchers took 34 people and gave psilocybin to half of them and a placebo to the other half. Even though there were some interesting subjective.

Pexel photo.
No content on this site, regardless of date, should be used to replace direct medical advice from your doctor or another trained practitioner.
Blogger Template Created by pipdig