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Thursday, November 2

What are the reasons for the frequent changes in medical guidelines?


Question.
I find it unsettling that guidelines and suggestions for medicine seem to change so frequently. For instance, I recently read that recommendations for colon cancer screening may undergo yet another modification. How exactly does one determine what is right?

Answer. Different factors contribute to the occurrence of these changes. One explanation for this is that continuing studies yield fresh data that informs new recommendations. An additional concern pertains to divergent expert opinions. As you correctly noted, this is exemplified by the controversy surrounding the optimal age to initiate colon cancer screening for individuals with an average risk profile this year.

  


A considerable number of clinicians, including myself, adhere to the recommendations put forth by the U.S. Preventive Services Task Force (USPSTF). The USPSTF enlists sixteen specialists from various fields to conduct research and discussion on the potential advantages and disadvantages of screening and other preventive and health-promoting techniques for each guideline. The summary recommendation is subsequently made available for public feedback.

Nevertheless, alternative professional organizations may assess the identical medical evidence, and the conclusions reached by their experts might diverge from those of the USPSTF. In contrast to clear-cut medical decisions, such as the administration of an antibiotic to treat strep throat, the vast majority of screening recommendations are formulated to address medical inquiries lacking an unequivocal, correct response.

Your concern regarding variations in colon cancer screening serves as a pertinent illustration. As the incidence of colon cancer among adults under the age of 50 increased, the USPSTF reduced the minimum age for screening to 45. Nevertheless, after analyzing the identical data, the American College of Physicians (ACP), a reputable organization, reached the conclusion that the potential risks of screening beyond age 50 were not weighed against the advantages.

Experts believe that colon cancer screening saves lives. Between the ages of 45 and 50, my favored approach advises all individuals with an average risk of colon cancer to undergo at least one colonoscopy. In the event that the initial colonoscopy yields normal results, you and your physician may jointly determine the subsequent screening regimen: stool testing every two years, colonoscopy every ten years, or sigmoidoscopy every five years in conjunction with stool testing.

As a matter of personal preference, I will persist in undergoing periodic screening colonoscopies. Two primary benefits are associated with colonoscopy. Polyp status, whether present or absent, contributes to the determination of my future colon cancer risk. Additionally, the early removal of a lesion or malignancy increases the probability that it will not progress into a significant issue.
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