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Monday, November 6

PSA testing for males continues to be excessive.


There are still too many PSA tests conducted on older men.

For males 70 years of age and older, the U.S. Preventive Services Task Force (USPSTF) advises avoiding regular prostate-specific antigen (PSA) testing. Nevertheless, two recent studies found that males in this age bracket continue to undergo too frequent PSA testing.

Researchers chose three million males who underwent routine PSA testing between 2003 and 2019 for the initial study, which appeared in Urology in April 2023. In comparison to younger men, males over the age of 70 were more likely to have high-frequency PSA testing, which is defined as testing more frequently than once every nine months.

The findings also demonstrated that, in comparison to older men examined less frequently, the older men with high-frequency testing had a considerably higher chance of undergoing prostate biopsies and being diagnosed with prostate cancer. The rates of early cancer therapy, however, were the same. This, according to the researchers, demonstrated that prostate biopsies did not significantly alter recommendations, even in cases where the results revealed malignancy.

On April 11, 2023, JAMA Network Open published a second study that surveyed over 32,000 men who were 70 years of age or older. Of the men in this age range, 55.3% had recently undergone a PSA screening. As people aged, the rate decreased, reaching 52.1% for those 75 to 79 and 39.4% for those 80 and above. Nevertheless, the study discovered that many men were still getting screening at ages older than those advised by the USPSTF, even though they would not benefit from routine PSA testing. The findings also revealed that older men often believe that PSA screening has more benefits than drawbacks. Any guy, regardless of age, should base his choice to continue PSA testing on a thoughtful conversation with his physician.
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